New study suggests fresh donor eggs have better chance of implantation than frozen

Researchers have presented a study to the American Society for Reproductive Medicine (ASRM) conference suggesting fresh donor eggs used during IVF have a higher chance of implantation than those that are frozen

Scientists from the University of Colorado and Duke University gave a talk at the event, which was held in San Antonio, Texas.

They also revealed the study showed that transferring just one embryo during IVF doubled the chances of IVF success

This bucks the historical method of transferring two or more embryos to increase the odds of pregnancy.

Senior study author Dr. Alex Polotsky of CU Advanced Reproductive Medicine said: “The most impressive finding that has relevance for all patients undergoing IVF is that performing the transfer with one embryo greatly increases the chance of a healthy baby, the desired objective in IVF.”

Researchers conducted this extensive study as they felt existing medical literature does not clearly indicate whether fresh or frozen donor eggs lead to better birth outcomes for patients undergoing IVF.

Their study examined a three-year swath of the latest available United States data reported to the Society for Assisted Reproductive Technology (SART)

This study looked at only those cycles that used eggs from donors in order to control for factors relating to egg quality. Donor eggs are known to provide the best chance of success for women undergoing IVF.

Among the examined cycles, healthy birth rates were similar with fresh and frozen eggs, with one important caveat. Double and triple embryo transfers were found to be significantly more prevalent among cycles using fresh donor eggs, leading to a higher incidence of multiple pregnancies (twins or more).

Multiple births are known to have increased risks of complications for both mother and child, including premature birth and low birth weight. When controlling for the factors known to affect IVF success, choosing to transfer just one embryo doubled the chance of a healthy baby, the desired objective in IVF.

The research team said frozen eggs provide a more economical and convenient way to obtain fertility treatment with donor eggs, while fresh eggs (non-frozen) tend to be more expensive and require the patient to coordinate with a single egg donor. Irrespective of the type of donor egg a patient pursues, opting for a single embryo transfer was shown to lead to a higher chance of a healthy pregnancy and birth.

Are you choosing whether to use donor eggs to begin or enhance your family? What do you think of the recommendations in this study? Email with your comments, or get in touch via social media, @IVFbabble

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