STAGE 2 | Down regulation for about 12-16 days

  • Approximately 20 days after stage 1, you will begin down regulation. This stage can take anywhere between 2-4 weeks and involves giving the doctor control of your ovaries by depriving the pituitary gland in the brain from controlling them. This is done with a course of GnRH analogue drugs.  This prepares the ovaries for external stimulation.
  • As soon as you start your next period, call your doctor and a baseline scan will be arranged for you, which will happen on day 2 to 5 of your period. You should be now be fully down regulated, meaning your ovaries are not actively developing eggs.
  • The baseline scan excludes cysts on the ovaries and polyps in the uterus and ensures that the lining is thin [approximately 3 mm] and that you are ready to start treatment.
  • Side effects: These drugs may cause some symptoms such as headaches, hot flushes, night sweats and mood swings. Not everyone suffers side effects though.
  • Please note: Treatment timelines will need to be adjusted based on how each patient responds to their medication.
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